Immunohistochemical analysis of laminin components in the blood-nerve barrier and blood-brain barrier
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چکیده
منابع مشابه
P45: The Role of Blood-Brain Barrier Breakdown Following Traumatic Brain in Post-Traumatic Epilepsy
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In autoimmune neurologic disorders, the blood-brain barrier (BBB) plays a central role in immunopathogenesis, since this vascular interface is an entry path for cells and effector molecules of the peripheral immune system to reach the target organ, the central nervous system (CNS). The BBB's unique anatomic structure and the tightly regulated interplay of its cellular and acellular components a...
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Introduction: Development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. Blood brain barrier (BBB) opening is an important part of edema named as vasogenic brain edema. In this study, quantitative alterations of BBB permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. Methods: Two groups of male rats (ischemic and sh...
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Blood Brain Barrier (BBB) is a specialized non fenestrate barrier that formation by the endothelial cells and controls the transportation of the cells and molecules in to the brain. Reducing in function of BBB is one of disruptions in neurological diseases like multiple sclerosis. Endothelial progenitor cell (EPC) help to the BBB to control the diapedesis of inflammatory cells & molecules in to...
متن کاملImmunohistochemical localization of adherens junction components in blood-brain barrier microvessels of the rat.
The morphology and molecular composition of intercellular adherens junctions have most frequently been described in epithelial cells and the fascia adhaerens of the intercalated disc. A group of cytoplasmic molecules is known to be associated with adherens junctions. The intercellular bond is mediated by cadherins which bridge the cells by homophilic binding. Recently, endothelial cells have al...
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ژورنال
عنوان ژورنال: Clinical and Experimental Neuroimmunology
سال: 2017
ISSN: 1759-1961
DOI: 10.1111/cen3.12359